His major league debut took place in August 27, 1995 with the White Sox. In 1997 he won a center field spot. He was traded to the Cincinnati Reds for Paul Konerko in 1998. Along with 3 other players he was traded to the Seattle Mariners for Ken Griffey Jr. before the 2000 season. He played in the All-Star Game in 2001 and has reached the postseason twice and won Gold Glove Awards in 2001 and 2003 for the quality of his defensive play. In 2004 he signed a three year, $19.5 million dollar contract to play center field for the Mets.
With the acquisition by the Mets of Carlos Beltran before the 2005 season, Cameron graciously surrendered his position to the star center fielder and has played most of his games in right field since. On August 11, 2005, in San Diego, Cameron collided with Beltran in the outfield as both made diving attempts to catch a fly ball. Cameron suffered multiple fractures of his nose and cheekbones and was removed from the field on a stretcher.
His former manager Jack McKeon has described him as "simply a delightful young man".
Together with Greg Brown and Robin Roberts he has written a book (aimed primarily at children) titled "It Takes a Team: Mike Cameron", ISBN 157243502X, where he presents his views on the importance of teamwork and describes his life. Published in 2002 by Triumph Books.
As he explains in the book, the keys to success are "self-confidence, open-mindedness, and teamwork".
- Height: 6 ft 2 in (1.88 m)
- Weight: 200 lb (91 kg)
- Bats: Right
- Throws: Right
- Position: CF